Landlord Letters Samples

Exercise

Ibuprofen is a common analgesic and anti-inflammatory found in commercial products by name Brufen, Algofen , Antalgil , Moment , etc..

The first commercial synthesis of ibuprofen (Figure 1) was carried out by the Boots Company PLC of Nottingham, UK. This synthesis, used since the 60s, is shown below. Regardless of the in-depth understanding of the chemistry of this synthesis, we can calculate its efficiency Atomic (EA) in order to get an idea of \u200b\u200bthe amount of waste products that accompany it (the atoms in gray are those who find themselves in the final product desired, ibuprofen, while those in black end up in waste products).

A new synthesis of ibuprofen (Figure 2) was developed by BHC Company (a joint venture between the Boots Company PLC and Hoechst Celanese Corporation). Note that the HF, the Raney nickel and Pd are used in catalytic amounts and therefore should not be included in the calculations of 'Atomic efficiency of the process of synthesis.

decision:

Using the parameters and decide which of the two syntheses is more beneficial for the environment (environmental performance above). The answer must be justified on the basis of the results of the calculation of the parameter EA.

Questions:

• parameter in the calculation of EA, what is the number to the numerator ?
• Each year, the United States alone, it produces about 16 million kg of ibuprofen. How kg of waste are produced with the two types of synthesis?